NOTCH3 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: Notch homolog 3
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 250-260 kDa, 100 kDa
Uniprot: Q9UM47
Gene id: 4854
Background: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain(NICD) it forms a transcriptional activator complex with RBPJ
RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs(By similarity).
Field of research: Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:500
Target: NOTCH3
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: Notch homolog 3
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 250-260 kDa, 100 kDa
Uniprot: Q9UM47
Gene id: 4854
Background: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain(NICD) it forms a transcriptional activator complex with RBPJ
RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs(By similarity).
Field of research: Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:500
Target: NOTCH3
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat