NLRP2 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: NLR family, pyrin domain containing 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 105-110 kDa
Uniprot: Q9NX02
Gene id: 55655
Background: Suppresses TNF-and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
Field of research: Immunology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200
Target: NLRP2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: NLR family, pyrin domain containing 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 105-110 kDa
Uniprot: Q9NX02
Gene id: 55655
Background: Suppresses TNF-and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
Field of research: Immunology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200
Target: NLRP2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse