NFE2 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: nuclear factor(erythroid-derived 2), 45kDa
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 45 kDa
Uniprot: Q16621
Gene id: 4778
Background: Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2(HS2) of the beta-globin control region(LCR). This subunit(NFE2) recognizes the TCAT
C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Field of research: Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF, IP
Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Target: NFE2
Purification: Immunogen affinity purified
Reactivity: Human
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: nuclear factor(erythroid-derived 2), 45kDa
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 45 kDa
Uniprot: Q16621
Gene id: 4778
Background: Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2(HS2) of the beta-globin control region(LCR). This subunit(NFE2) recognizes the TCAT
C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Field of research: Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF, IP
Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Target: NFE2
Purification: Immunogen affinity purified
Reactivity: Human