NF2 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: neurofibromin 2(merlin)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 66-70 kDa
Uniprot: P35240
Gene id: 4771
Background: Probable regulator of the Hippo
SWH(Sav
Wts
Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo
SWH(Sav
Wts
Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP
DCAF1 E3 ubiquitin-protein ligase complex.
Field of research: Stem Cells
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC,IP,IF
Dilution: WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500
Target: NF2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
![]()
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: neurofibromin 2(merlin)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 66-70 kDa
Uniprot: P35240
Gene id: 4771
Background: Probable regulator of the Hippo
SWH(Sav
Wts
Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo
SWH(Sav
Wts
Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP
DCAF1 E3 ubiquitin-protein ligase complex.
Field of research: Stem Cells
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC,IP,IF
Dilution: WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500
Target: NF2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat