NENF antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 7C8
Isotype: IgG2a
Immunogen: neuron derived neurotrophic factor
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 18 kDa
Uniprot: Q9UMX5
Gene id: 29937
Background: Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1
ERK2, MAPK3
ERK1 and AKT1
AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance(By similarity). Plays a role in the human tumorigenesis(PubMed:22748190).
Field of research: Neuroscience
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB,IF
Dilution: WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:500
Target: NENF
Purification: Protein A+G purification
Reactivity: Human, Mouse
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Clonality: Monoclonal
Clone: 7C8
Isotype: IgG2a
Immunogen: neuron derived neurotrophic factor
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 18 kDa
Uniprot: Q9UMX5
Gene id: 29937
Background: Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1
ERK2, MAPK3
ERK1 and AKT1
AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance(By similarity). Plays a role in the human tumorigenesis(PubMed:22748190).
Field of research: Neuroscience
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB,IF
Dilution: WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:500
Target: NENF
Purification: Protein A+G purification
Reactivity: Human, Mouse