CDH2 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 1G1
Isotype: IgG2a
Immunogen: cadherin 2, type 1, N-cadherin(neuronal)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 130 kDa
Uniprot: P19022
Gene id: 1000
Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density(By similarity).
Field of research: Signal Transduction, Cardiovascular, Immunology, Neuroscience, Stem Cells
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB
Dilution: WB: 1:1000-1:10000; IHC: 1:20-1:200
Target: CDH2
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat
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Clonality: Monoclonal
Clone: 1G1
Isotype: IgG2a
Immunogen: cadherin 2, type 1, N-cadherin(neuronal)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 130 kDa
Uniprot: P19022
Gene id: 1000
Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density(By similarity).
Field of research: Signal Transduction, Cardiovascular, Immunology, Neuroscience, Stem Cells
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB
Dilution: WB: 1:1000-1:10000; IHC: 1:20-1:200
Target: CDH2
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat