MPZL1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: myelin protein zero-like 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 16 kDa
Uniprot: O95297
Gene id: 9019
Background: Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11
SHP-2 to the cell membrane and is a putative substrate of PTPN11
SHP-2. Is a major receptor for concanavalin-A(ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.
Field of research: Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: MPZL1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: myelin protein zero-like 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 16 kDa
Uniprot: O95297
Gene id: 9019
Background: Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11
SHP-2 to the cell membrane and is a putative substrate of PTPN11
SHP-2. Is a major receptor for concanavalin-A(ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.
Field of research: Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: MPZL1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat