MME antibody - 100 µg

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Host : Mouse
Clonality: Monoclonal
Clone: 1H6
Isotype: IgG2a
Immunogen: membrane metallo-endopeptidase
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 90-110 kDa
Uniprot: P08473
Gene id: 4311
Background: MME is also names as neprilysin,CALLA,NEP,SFE,CD10 and belongs to the peptidase M13 family.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.CD10 has been considered a useful marker in the diagnosis of renal carcinomas, because of its expression in clear cell and papillary renal cell carcinomas and its absence in chromophobe renal cell carcinomas(PMID:15286660).This antibody is specific to MME.
Field of research: Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Neuroscience, Stem Cells
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB
Dilution: WB: 1:500-1:5000; IHC: 1:20-1:200
Target: MME
Purification: Protein A+G purification
Reactivity: Human, Pig

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