MITF antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: microphthalmia-associated transcription factor
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 60-65 kDa
Uniprot: O75030
Gene id: 4286
Background: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences(E-boxes)(5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase(TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase(TYR) and tyrosinase-related protein 1(TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Field of research: Epigenetics, Metabolism, Immunology, Developmental biology, Neuroscience
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, FC, IP
Dilution: WB: 1:500-1:2000; IP: 1:500-1:2000
Target: MITF
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: microphthalmia-associated transcription factor
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 60-65 kDa
Uniprot: O75030
Gene id: 4286
Background: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences(E-boxes)(5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase(TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase(TYR) and tyrosinase-related protein 1(TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Field of research: Epigenetics, Metabolism, Immunology, Developmental biology, Neuroscience
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, FC, IP
Dilution: WB: 1:500-1:2000; IP: 1:500-1:2000
Target: MITF
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat