MGMT antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: O-6-methylguanine-DNA methyltransferase
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 22 kDa
Uniprot: P16455
Gene id: 4255
Background: Involved in the cellular defense against the biological effects of O6-methylguanine(O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Field of research: Cancer, Immunology, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:20-1:200
Target: MGMT
Purification: Immunogen affinity purified
Reactivity: Human
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: O-6-methylguanine-DNA methyltransferase
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 22 kDa
Uniprot: P16455
Gene id: 4255
Background: Involved in the cellular defense against the biological effects of O6-methylguanine(O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Field of research: Cancer, Immunology, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:20-1:200
Target: MGMT
Purification: Immunogen affinity purified
Reactivity: Human