MEN1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: multiple endocrine neoplasia I
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 63-70 kDa
Uniprot: O00255
Gene id: 4221
Background: Essential component of a MLL
SET1 histone methyltransferase(HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3(H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression(By similarity). May be involved in DNA repair.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: MEN1
Purification: Immunogen affinity purified
Reactivity: Human
![]()
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: multiple endocrine neoplasia I
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 63-70 kDa
Uniprot: O00255
Gene id: 4221
Background: Essential component of a MLL
SET1 histone methyltransferase(HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3(H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression(By similarity). May be involved in DNA repair.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: MEN1
Purification: Immunogen affinity purified
Reactivity: Human