MCM7 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: minichromosome maintenance complex component 7
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 81 kDa
Uniprot: P33993
Gene id: 4176
Background: Acts as component of the MCM2-7 complex(MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage.
Field of research: Cancer, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP, IHC
Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Target: MCM7
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: minichromosome maintenance complex component 7
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 81 kDa
Uniprot: P33993
Gene id: 4176
Background: Acts as component of the MCM2-7 complex(MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage.
Field of research: Cancer, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP, IHC
Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Target: MCM7
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat