MAGEC2 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: melanoma antigen family C, 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 41 kDa
Uniprot: Q9UBF1
Gene id: 51438
Background: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53
TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53
TP53 degradation. Proposed to act through recruitment and
or stabilization of the Ubl-conjugating enzymes(E2) at the E3:substrate complex.
Field of research: Cancer, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC
Dilution: IHC: 1:20 - 1:200
Target: MAGEC2
Purification: Immunogen affinity purified
Reactivity: Human
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: melanoma antigen family C, 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 41 kDa
Uniprot: Q9UBF1
Gene id: 51438
Background: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53
TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53
TP53 degradation. Proposed to act through recruitment and
or stabilization of the Ubl-conjugating enzymes(E2) at the E3:substrate complex.
Field of research: Cancer, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC
Dilution: IHC: 1:20 - 1:200
Target: MAGEC2
Purification: Immunogen affinity purified
Reactivity: Human