MAGEA3 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 4E9
Isotype: IgG2a
Immunogen: melanoma antigen family A, 3
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 35-55 kDa
Uniprot: P43357
Gene id: 4102
Background: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53
TP53 ubiquitination by TRIM28. Proposed to act through recruitment and
or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Field of research: Cancer, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
Target: MAGEA3
Purification: Protein A+G purification
Reactivity: Human
![]()
Clonality: Monoclonal
Clone: 4E9
Isotype: IgG2a
Immunogen: melanoma antigen family A, 3
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 35-55 kDa
Uniprot: P43357
Gene id: 4102
Background: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53
TP53 ubiquitination by TRIM28. Proposed to act through recruitment and
or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Field of research: Cancer, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
Target: MAGEA3
Purification: Protein A+G purification
Reactivity: Human