MADCAM1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: mucosal vascular addressin cell adhesion molecule 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 40 kDa
Uniprot: Q13477
Gene id: 8174
Background: Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4
beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4
beta-7-dependent adhesion strengthening, independent of L-selectin binding.
Field of research: Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC
Dilution: IHC: 1:20-1:200
Target: MADCAM1
Purification: Immunogen affinity purified
Reactivity: Human
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: mucosal vascular addressin cell adhesion molecule 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 40 kDa
Uniprot: Q13477
Gene id: 8174
Background: Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4
beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4
beta-7-dependent adhesion strengthening, independent of L-selectin binding.
Field of research: Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC
Dilution: IHC: 1:20-1:200
Target: MADCAM1
Purification: Immunogen affinity purified
Reactivity: Human