LGI1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: leucine-rich, glioma inactivated 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 64 kDa, 58 kDa
Uniprot: O95970
Gene id: 9211
Background: Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors(By similarity). Plays a role in suppressing the production of MMP1
3 through the phosphatidylinositol 3-kinase
ERK pathway. May play a role in the control of neuroblastoma cell survival.
Field of research: Neuroscience, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
Target: LGI1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: leucine-rich, glioma inactivated 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 64 kDa, 58 kDa
Uniprot: O95970
Gene id: 9211
Background: Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors(By similarity). Plays a role in suppressing the production of MMP1
3 through the phosphatidylinositol 3-kinase
ERK pathway. May play a role in the control of neuroblastoma cell survival.
Field of research: Neuroscience, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000; IHC: 1:50-1:200
Target: LGI1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat