LAT antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: linker for activation of T cells
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 36-38 kDa
Uniprot: O43561
Gene id: 27040
Background: Required for TCR(T-cell antigen receptor)-and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3(low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1(high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
Field of research: Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:200-1:1000; IHC: 1:20-1:200
Target: LAT
Purification: Immunogen affinity purified
Reactivity: Human, Mouse
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: linker for activation of T cells
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 36-38 kDa
Uniprot: O43561
Gene id: 27040
Background: Required for TCR(T-cell antigen receptor)-and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3(low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1(high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
Field of research: Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:200-1:1000; IHC: 1:20-1:200
Target: LAT
Purification: Immunogen affinity purified
Reactivity: Human, Mouse