LMNB1 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 4A4
Isotype: IgG2a
Immunogen: lamin B1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 66 kDa
Uniprot: P20700
Gene id: 4001
Background: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. This protein is not suitable for samples where the nuclear envelope has been removed.
Field of research: Stem Cells, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF, FC, IP
Dilution: WB: 1:500-1:2000; IP: 1:5000-1:50000 ; IHC: 1:500-1:2000; IF: 1:50-1:500
Target: LMNB1
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat
![]()
Clonality: Monoclonal
Clone: 4A4
Isotype: IgG2a
Immunogen: lamin B1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 66 kDa
Uniprot: P20700
Gene id: 4001
Background: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. This protein is not suitable for samples where the nuclear envelope has been removed.
Field of research: Stem Cells, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF, FC, IP
Dilution: WB: 1:500-1:2000; IP: 1:5000-1:50000 ; IHC: 1:500-1:2000; IF: 1:50-1:500
Target: LMNB1
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat