KDM5C antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: lysine(K)-specific demethylase 5C
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 171-180 kDa
Uniprot: P41229
Gene id: 8242
Background: Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL
BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2(By similarity).
Field of research: Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: KDM5C
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
![]()
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: lysine(K)-specific demethylase 5C
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 171-180 kDa
Uniprot: P41229
Gene id: 8242
Background: Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL
BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2(By similarity).
Field of research: Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: KDM5C
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat