IRF8 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: interferon regulatory factor 8
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 50 kDa
Uniprot: Q02556
Gene id: 3394
Background: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes(the interferon consensus sequence(ICS)). Plays a negative regulatory role in cells of the immune system. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence(5'-TGAnTCA
GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes(By similarity).
Field of research: Epigenetics, Cancer, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: IRF8
Purification: Immunogen affinity purified
Reactivity: Human
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: interferon regulatory factor 8
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 50 kDa
Uniprot: Q02556
Gene id: 3394
Background: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes(the interferon consensus sequence(ICS)). Plays a negative regulatory role in cells of the immune system. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence(5'-TGAnTCA
GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes(By similarity).
Field of research: Epigenetics, Cancer, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: IRF8
Purification: Immunogen affinity purified
Reactivity: Human