IL4 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 5A0
Isotype: IgG2a
Immunogen: interleukin 4
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 18 kDa
Uniprot: P05112
Gene id: 3565
Background: Participates in at least several B-cell activation processes as well as of other cell types(PubMed:3016727). It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE(CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages(By similarity).
Field of research: Immunology, Cardiovascular, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:5000; IHC: 1:20-1:200
Target: IL4
Purification: Protein A+G purification
Reactivity: Human, rat
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Clonality: Monoclonal
Clone: 5A0
Isotype: IgG2a
Immunogen: interleukin 4
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 18 kDa
Uniprot: P05112
Gene id: 3565
Background: Participates in at least several B-cell activation processes as well as of other cell types(PubMed:3016727). It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE(CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages(By similarity).
Field of research: Immunology, Cardiovascular, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:5000; IHC: 1:20-1:200
Target: IL4
Purification: Protein A+G purification
Reactivity: Human, rat