IL10RB antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: interleukin 10 receptor, beta
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 42-45 kDa
Uniprot: Q08334
Gene id: 3588
Background: Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1
IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand
receptor complex stimulate the activation of the JAK
STAT signaling pathway leading to the expression of IFN-stimulated genes(ISG), which contribute to the antiviral state.
Field of research: Immunology, Cardiovascular, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: IL10RB
Purification: Immunogen affinity purified
Reactivity: Human
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: interleukin 10 receptor, beta
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 42-45 kDa
Uniprot: Q08334
Gene id: 3588
Background: Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1
IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand
receptor complex stimulate the activation of the JAK
STAT signaling pathway leading to the expression of IFN-stimulated genes(ISG), which contribute to the antiviral state.
Field of research: Immunology, Cardiovascular, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: IL10RB
Purification: Immunogen affinity purified
Reactivity: Human