IL1B antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 9G5
Isotype: IgG1
Immunogen: interleukin 1, beta
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 35 kDa
Uniprot: P01584
Gene id: 3553
Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1
ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2
COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Field of research: Neuroscience, Immunology, Cardiovascular, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB
Dilution: WB: 1:1000-1:4000; IHC: 1:50-1:500
Target: IL1B
Purification: Protein G purified
Reactivity: Human
![]()
Clonality: Monoclonal
Clone: 9G5
Isotype: IgG1
Immunogen: interleukin 1, beta
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 35 kDa
Uniprot: P01584
Gene id: 3553
Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1
ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2
COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Field of research: Neuroscience, Immunology, Cardiovascular, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB
Dilution: WB: 1:1000-1:4000; IHC: 1:50-1:500
Target: IL1B
Purification: Protein G purified
Reactivity: Human