IDS antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 2D2
Isotype: IgG1
Immunogen: iduronate 2-sulfatase
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 76 kDa, 55 kDa
Uniprot: P22304
Gene id: 3423
Background: Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is synthesized as two precursor forms of 76 and 90 kDa that are converted, through a 62 kDa intermediate, to 55 and 45 kDa mature polypeptides due to an internal proteolytic cleavage (PMID: 10838181).
Field of research: Cardiovascular, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Target: IDS
Purification: Protein A+G purification
Reactivity: Human
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Clonality: Monoclonal
Clone: 2D2
Isotype: IgG1
Immunogen: iduronate 2-sulfatase
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 76 kDa, 55 kDa
Uniprot: P22304
Gene id: 3423
Background: Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is synthesized as two precursor forms of 76 and 90 kDa that are converted, through a 62 kDa intermediate, to 55 and 45 kDa mature polypeptides due to an internal proteolytic cleavage (PMID: 10838181).
Field of research: Cardiovascular, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Target: IDS
Purification: Protein A+G purification
Reactivity: Human