IDH1 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 1G10
Isotype: IgG1
Immunogen: isocitrate dehydrogenase 1(NADP+), soluble
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 46 kDa
Uniprot: O75874
Gene id: 3417
Background: IDH1, also named as PICD and IDP, belongs to the isocitrate and isopropylmalate dehydrogenases family. It is a common feature of a major subset of primary human brain cancers. It can form a homodimer(PMID:15173171).IDH1 mutation is always heterozygotic and IDH1 functions as a dimer, theoretically there will be 25% each wild type and mutant homo-dimers and 50% hetero-dimers present in the tumor cells(PMID:21079649 ).
Field of research: Cancer, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500
Target: IDH1
Purification: Protein A+G purification
Reactivity: Human
Clonality: Monoclonal
Clone: 1G10
Isotype: IgG1
Immunogen: isocitrate dehydrogenase 1(NADP+), soluble
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 46 kDa
Uniprot: O75874
Gene id: 3417
Background: IDH1, also named as PICD and IDP, belongs to the isocitrate and isopropylmalate dehydrogenases family. It is a common feature of a major subset of primary human brain cancers. It can form a homodimer(PMID:15173171).IDH1 mutation is always heterozygotic and IDH1 functions as a dimer, theoretically there will be 25% each wild type and mutant homo-dimers and 50% hetero-dimers present in the tumor cells(PMID:21079649 ).
Field of research: Cancer, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500
Target: IDH1
Purification: Protein A+G purification
Reactivity: Human