ICOS antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: inducible T-cell co-stimulator
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 28 kDa, 45-50 kDa
Uniprot: Q9Y6W8
Gene id: 29851
Background: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes(By similarity).
Field of research: Cancer, Immunology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: ICOS
Purification: Immunogen affinity purified
Reactivity: Human
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: inducible T-cell co-stimulator
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 28 kDa, 45-50 kDa
Uniprot: Q9Y6W8
Gene id: 29851
Background: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes(By similarity).
Field of research: Cancer, Immunology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: ICOS
Purification: Immunogen affinity purified
Reactivity: Human