ICAM1 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 7F11
Isotype: IgG1
Immunogen: intercellular adhesion molecule 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 85-95 kDa
Uniprot: P05362
Gene id: 3383
Background: ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056). It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624; 2538244; 2475784).
Field of research: Stem Cells, Immunology, Cardiovascular
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB, FC
Dilution: WB: 1:1000-1:4000; IHC: 1:50-1:500
Target: ICAM1
Purification: Protein A+G purification
Reactivity: Human
Clonality: Monoclonal
Clone: 7F11
Isotype: IgG1
Immunogen: intercellular adhesion molecule 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 85-95 kDa
Uniprot: P05362
Gene id: 3383
Background: ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056). It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624; 2538244; 2475784).
Field of research: Stem Cells, Immunology, Cardiovascular
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB, FC
Dilution: WB: 1:1000-1:4000; IHC: 1:50-1:500
Target: ICAM1
Purification: Protein A+G purification
Reactivity: Human