HTRA2 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: HtrA serine peptidase 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 36 kDa
Uniprot: O43464
Gene id: 27429
Background: Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins(also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.
Field of research: Neuroscience, Signal Transduction, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200
Target: HTRA2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat, Monkey
![]()
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: HtrA serine peptidase 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 36 kDa
Uniprot: O43464
Gene id: 27429
Background: Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins(also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.
Field of research: Neuroscience, Signal Transduction, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200
Target: HTRA2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat, Monkey