HINT1 antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: histidine triad nucleotide binding protein 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 14 kDa
Uniprot: P49773
Gene id: 3094
Background: Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5'monophosphoramidate(AMP-NH2), adenosine 5'monophosphomorpholidate(AMP-morpholidate) and guanosine 5'monophosphomorpholidate(GMP-morpholidate). Hydrolyzes lysyl-AMP(AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP(GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide. In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1
TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53
TP53 levels and p53
TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF(SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.
Field of research: Signal Transduction, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Target: HINT1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat

222.50 € 222.5 EUR 222.50 € VAT Excluded

222.50 € VAT Excluded

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