GZMB antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: granzyme B
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 33 kDa
Uniprot: P10144
Gene id: 3002
Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases(aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3,-7,-9 and 10 to give rise to active enzymes mediating apoptosis.
Field of research: Cancer, Immunology, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500
Target: GZMB
Purification: Immunogen affinity purified
Reactivity: Human
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: granzyme B
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 33 kDa
Uniprot: P10144
Gene id: 3002
Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases(aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3,-7,-9 and 10 to give rise to active enzymes mediating apoptosis.
Field of research: Cancer, Immunology, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500
Target: GZMB
Purification: Immunogen affinity purified
Reactivity: Human