GSDMD antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: gasdermin D
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 50-53 kDa
Uniprot: P57764
Gene id: 79792
Background: GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Field of research: Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Target: GSDMD
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: gasdermin D
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 50-53 kDa
Uniprot: P57764
Gene id: 79792
Background: GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Field of research: Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Target: GSDMD
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat