GRB7 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: growth factor receptor-bound protein 7
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 60-70 kDa
Uniprot: Q14451
Gene id: 2886
Background: Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and
or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress(By similarity).
Field of research: Cardiovascular, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP
Dilution: WB: 1:500-1:2000; IP: 1:200-1:2000
Target: GRB7
Purification: Immunogen affinity purified
Reactivity: Human, Mouse
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: growth factor receptor-bound protein 7
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 60-70 kDa
Uniprot: Q14451
Gene id: 2886
Background: Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and
or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress(By similarity).
Field of research: Cardiovascular, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP
Dilution: WB: 1:500-1:2000; IP: 1:200-1:2000
Target: GRB7
Purification: Immunogen affinity purified
Reactivity: Human, Mouse