GOT1 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 2F1
Isotype: IgG2a
Immunogen: glutamic-oxaloacetic transaminase 1, soluble(aspartate aminotransferase 1)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 43 kDa
Uniprot: P17174
Gene id: 2805
Background: Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase(3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.
Field of research: Neuroscience, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200
Target: GOT1
Purification: Protein A+G purification
Reactivity: Human
Clonality: Monoclonal
Clone: 2F1
Isotype: IgG2a
Immunogen: glutamic-oxaloacetic transaminase 1, soluble(aspartate aminotransferase 1)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 43 kDa
Uniprot: P17174
Gene id: 2805
Background: Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase(3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.
Field of research: Neuroscience, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200
Target: GOT1
Purification: Protein A+G purification
Reactivity: Human