GM2A antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 9C9
Isotype: IgG2a
Immunogen: GM2 ganglioside activator
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 22 kDa
Uniprot: P17900
Gene id: 2760
Background: The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity(By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:1000
Target: GM2A
Purification: Protein A+G purification
Reactivity: Human
Clonality: Monoclonal
Clone: 9C9
Isotype: IgG2a
Immunogen: GM2 ganglioside activator
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 22 kDa
Uniprot: P17900
Gene id: 2760
Background: The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity(By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:1000
Target: GM2A
Purification: Protein A+G purification
Reactivity: Human