FN1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: fibronectin 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 260 kDa
Uniprot: P02751
Gene id: 2335
Background: Fibronectin 1(FN1) is a high molecular weight glycoprotein which exists in both a soluble form in plasma(plasma FN1) and other body fluids and an insoluble form in the extracellular matrix(cellular FN1). Plasma FN1(dimeric form) is secreted by hepatocytes. Cellular FN(dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen, fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis, wound healing, hemostasis, host defense, and metastasis.(PMID: 7276612; 12244123; 12847088)
Field of research: Stem Cells, Cancer, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:200-1:5000; IHC: 1:50-1:200
Target: FN1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: fibronectin 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 260 kDa
Uniprot: P02751
Gene id: 2335
Background: Fibronectin 1(FN1) is a high molecular weight glycoprotein which exists in both a soluble form in plasma(plasma FN1) and other body fluids and an insoluble form in the extracellular matrix(cellular FN1). Plasma FN1(dimeric form) is secreted by hepatocytes. Cellular FN(dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen, fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis, wound healing, hemostasis, host defense, and metastasis.(PMID: 7276612; 12244123; 12847088)
Field of research: Stem Cells, Cancer, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:200-1:5000; IHC: 1:50-1:200
Target: FN1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat