FBXO7 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: F-box protein 7
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 58.5 kDa
Uniprot: Q9Y3I1
Gene id: 25793
Background: Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy(mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.
Field of research: Neuroscience, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Target: FBXO7
Purification: Immunogen affinity purified
Reactivity: Human, Mouse
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: F-box protein 7
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 58.5 kDa
Uniprot: Q9Y3I1
Gene id: 25793
Background: Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy(mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.
Field of research: Neuroscience, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Target: FBXO7
Purification: Immunogen affinity purified
Reactivity: Human, Mouse