ERBB4 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 180 kDa
Uniprot: Q15303
Gene id: 2066
Background: This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Field of research: Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB
Dilution: WB: 1:500 - 1:1000; IHC: 1:50 - 1:100
Target: ERBB4
Purification: Immunogen affinity purified
Reactivity: Mouse, Rat
![]()
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 180 kDa
Uniprot: Q15303
Gene id: 2066
Background: This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Field of research: Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC, WB
Dilution: WB: 1:500 - 1:1000; IHC: 1:50 - 1:100
Target: ERBB4
Purification: Immunogen affinity purified
Reactivity: Mouse, Rat