ERBB3 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: v-erb-b2 erythroblastic leukemia viral oncogene homolog 3
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight:
Uniprot: P21860
Gene id: 2065
Background: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1(NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase(PubMed:20682778). May also be activated by CSPG5(PubMed:15358134).
Field of research: Signal Transduction, Metabolism, Cardiovascular, Cancer, Immunology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC
Dilution: IHC: 1:50-1:500
Target: ERBB3
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: v-erb-b2 erythroblastic leukemia viral oncogene homolog 3
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight:
Uniprot: P21860
Gene id: 2065
Background: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1(NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase(PubMed:20682778). May also be activated by CSPG5(PubMed:15358134).
Field of research: Signal Transduction, Metabolism, Cardiovascular, Cancer, Immunology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IHC
Dilution: IHC: 1:50-1:500
Target: ERBB3
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat