HSD17B10 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 6C4
Isotype: IgG1
Immunogen: hydroxysteroid(17-beta) dehydrogenase 10
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 27 kDa
Uniprot: Q99714
Gene id: 3028
Background: Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1
TRMT10C, MRPP2
HSD17B10 and MRPP3
KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease(AD).
Field of research: Signal Transduction, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:1000-1:4000
Target: HSD17B10
Purification: Protein A+G purification
Reactivity: Human, Mouse
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Clonality: Monoclonal
Clone: 6C4
Isotype: IgG1
Immunogen: hydroxysteroid(17-beta) dehydrogenase 10
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 27 kDa
Uniprot: Q99714
Gene id: 3028
Background: Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1
TRMT10C, MRPP2
HSD17B10 and MRPP3
KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease(AD).
Field of research: Signal Transduction, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:1000-1:4000
Target: HSD17B10
Purification: Protein A+G purification
Reactivity: Human, Mouse