COL18A1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: collagen, type XVIII, alpha 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 19 kDa, 27 kDa
Uniprot: P39060
Gene id:
Background: Endostatin is a naturally-occurring 20-kDa C-terminal fragment derived from COL18A1(also named as KNO). It is reported to serve as an anti-angiogenic agent, similar to angiostatin and thrombospondin. It potently inhibits endothelial cell proliferation and inhibits endothelial cell angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling. Endostatin is a broad spectrum angiogenesis inhibitor and may interfere with the pro-angiogenic action of growth factors such as basic fibroblast growth factor(bFGF
FGF-2) and vascular endothelial growth factor(VEGF).
Field of research: Cardiovascular, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:200-1:1000; IHC: 1:20-1:200
Target: COL18A1
Purification: Immunogen affinity purified
Reactivity: Human
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: collagen, type XVIII, alpha 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 19 kDa, 27 kDa
Uniprot: P39060
Gene id:
Background: Endostatin is a naturally-occurring 20-kDa C-terminal fragment derived from COL18A1(also named as KNO). It is reported to serve as an anti-angiogenic agent, similar to angiostatin and thrombospondin. It potently inhibits endothelial cell proliferation and inhibits endothelial cell angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling. Endostatin is a broad spectrum angiogenesis inhibitor and may interfere with the pro-angiogenic action of growth factors such as basic fibroblast growth factor(bFGF
FGF-2) and vascular endothelial growth factor(VEGF).
Field of research: Cardiovascular, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:200-1:1000; IHC: 1:20-1:200
Target: COL18A1
Purification: Immunogen affinity purified
Reactivity: Human