ENG antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: endoglin
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 68-75 kDa, 170-180 kDa
Uniprot: P17813
Gene id: 2022
Background: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Field of research: Signal Transduction, Cardiovascular, Immunology, Cancer, Developmental biology, Stem Cells
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP, IHC
Dilution: WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:2000-1:8000
Target: ENG
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: endoglin
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 68-75 kDa, 170-180 kDa
Uniprot: P17813
Gene id: 2022
Background: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Field of research: Signal Transduction, Cardiovascular, Immunology, Cancer, Developmental biology, Stem Cells
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP, IHC
Dilution: WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:2000-1:8000
Target: ENG
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat