DLL4 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: delta-like 4(Drosophila)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 75-80 kDa
Uniprot: Q9NR61
Gene id: 54567
Background: Involved in the Notch signaling pathway as Notch ligand(PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting(PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types(By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate(PubMed:17728344).
Field of research: Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology, Stem Cells, Cell Division and Proliferation
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP
Dilution: WB: 1:500-1:2000; IP: 1:200-1:2000
Target: DLL4
Purification: Immunogen affinity purified
Reactivity: Human, Mouse
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: delta-like 4(Drosophila)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 75-80 kDa
Uniprot: Q9NR61
Gene id: 54567
Background: Involved in the Notch signaling pathway as Notch ligand(PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting(PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types(By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate(PubMed:17728344).
Field of research: Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology, Stem Cells, Cell Division and Proliferation
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP
Dilution: WB: 1:500-1:2000; IP: 1:200-1:2000
Target: DLL4
Purification: Immunogen affinity purified
Reactivity: Human, Mouse