DENND1A antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: DENN
MADD domain containing 1A
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 111 kDa, 64 kDa
Uniprot: Q8TEH3
Gene id: 57706
Background: Guanine nucleotide exchange factor(GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes(PubMed:20154091, PubMed:20937701). Binds phosphatidylinositol-phosphates(PtdInsPs), with some preference for PtdIns(3)P(By similarity).
Field of research: Neuroscience
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF
Dilution: WB: 1:500-1:2000; IF: 1:20-1:200
Target: DENND1A
Purification: Immunogen affinity purified
Reactivity: Human
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: DENN
MADD domain containing 1A
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 111 kDa, 64 kDa
Uniprot: Q8TEH3
Gene id: 57706
Background: Guanine nucleotide exchange factor(GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes(PubMed:20154091, PubMed:20937701). Binds phosphatidylinositol-phosphates(PtdInsPs), with some preference for PtdIns(3)P(By similarity).
Field of research: Neuroscience
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF
Dilution: WB: 1:500-1:2000; IF: 1:20-1:200
Target: DENND1A
Purification: Immunogen affinity purified
Reactivity: Human