KRT19 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 2F9
Isotype: IgG2a
Immunogen: keratin 19
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 44-50 kDa
Uniprot: P08727
Gene id: 3880
Background: The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. KRT19, one of type I keratins, is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Due to its high sensitivity, KRT19 is the most used marker for detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. This antibody, generated against full length KRT19 protein, also recognizes KRT17, another type I keratin homologous to KRT19. KRT17 is used as a marker for trauma.
Field of research: Stem Cells, Immunology, Cancer
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:5000; IHC: 1:50-1:500
Target: KRT19
Purification: Protein A+G purification
Reactivity: Human
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Clonality: Monoclonal
Clone: 2F9
Isotype: IgG2a
Immunogen: keratin 19
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 44-50 kDa
Uniprot: P08727
Gene id: 3880
Background: The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. KRT19, one of type I keratins, is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Due to its high sensitivity, KRT19 is the most used marker for detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. This antibody, generated against full length KRT19 protein, also recognizes KRT17, another type I keratin homologous to KRT19. KRT17 is used as a marker for trauma.
Field of research: Stem Cells, Immunology, Cancer
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:5000; IHC: 1:50-1:500
Target: KRT19
Purification: Protein A+G purification
Reactivity: Human