CUX1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: cut-like homeobox 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 80 kDa
Uniprot: P39880
Gene id: 1523
Background: Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions(MARs)(5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor(TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator(By similarity).
Field of research: Neuroscience, Cardiovascular, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF, IHC, IP
Dilution: WB: 1:1000-1:3000; IP:1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100
Target: CUX1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: cut-like homeobox 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 80 kDa
Uniprot: P39880
Gene id: 1523
Background: Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions(MARs)(5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor(TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator(By similarity).
Field of research: Neuroscience, Cardiovascular, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IF, IHC, IP
Dilution: WB: 1:1000-1:3000; IP:1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100
Target: CUX1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat