COMMD5 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: COMM domain containing 5
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 25-28 kDa
Uniprot: Q9GZQ3
Gene id: 54951
Background: May modulate activity of cullin-RING E3 ubiquitin ligase(CRL) complexes(PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2
M phase transition probably by transactivating p21
CDKN1A through the p53
TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis(By similarity). Down-regulates activation of NF-kappa-B(PubMed:15799966).
Field of research: Signal Transduction, Metabolism, Epigenetics
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP
Dilution: WB: 1:500-1:2000; IP: 1:200-1:2000
Target: COMMD5
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: COMM domain containing 5
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 25-28 kDa
Uniprot: Q9GZQ3
Gene id: 54951
Background: May modulate activity of cullin-RING E3 ubiquitin ligase(CRL) complexes(PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2
M phase transition probably by transactivating p21
CDKN1A through the p53
TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis(By similarity). Down-regulates activation of NF-kappa-B(PubMed:15799966).
Field of research: Signal Transduction, Metabolism, Epigenetics
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP
Dilution: WB: 1:500-1:2000; IP: 1:200-1:2000
Target: COMMD5
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat