MYC antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: v-myc myelocytomatosis viral oncogene homolog(avian)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 62-65 kDa, 50 kDa
Uniprot: P01106
Gene id:
Background: MYC contains one basic helix-loop-helix(bHLH) domain. This protein is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. It seems to activate the transcription of growth-related genes. It binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. This antibody is a rabbit polyclonal antibody raised against recombinant protein of human MYC.The 50kDa band recognized by antibody is the native form of MYC, while the other bands, between 60-70kDa, are the phosphorylated form of MYC [PMID: 12189186]
Field of research: Epigenetics, Metabolism, Immunology, Cancer, Neuroscience, Stem Cells, Cell Division and Proliferation
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP, IHC
Dilution: WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:50-1:200
Target: MYC
Purification: Immunogen affinity purified
Reactivity: Human, Mouse
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: v-myc myelocytomatosis viral oncogene homolog(avian)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 62-65 kDa, 50 kDa
Uniprot: P01106
Gene id:
Background: MYC contains one basic helix-loop-helix(bHLH) domain. This protein is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. It seems to activate the transcription of growth-related genes. It binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. This antibody is a rabbit polyclonal antibody raised against recombinant protein of human MYC.The 50kDa band recognized by antibody is the native form of MYC, while the other bands, between 60-70kDa, are the phosphorylated form of MYC [PMID: 12189186]
Field of research: Epigenetics, Metabolism, Immunology, Cancer, Neuroscience, Stem Cells, Cell Division and Proliferation
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP, IHC
Dilution: WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:50-1:200
Target: MYC
Purification: Immunogen affinity purified
Reactivity: Human, Mouse