CASP1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: caspase 1, apoptosis-related cysteine peptidase(interleukin 1, beta, convertase)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 45-47 kDa, 30 kDa, 35 kDa
Uniprot: P29466
Gene id: 834
Background: CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta(IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products(PMID:21804020). It has 5 isoforms produced by alternative splicing.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000;IHC: 1:20-1:200
Target: CASP1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: caspase 1, apoptosis-related cysteine peptidase(interleukin 1, beta, convertase)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 45-47 kDa, 30 kDa, 35 kDa
Uniprot: P29466
Gene id: 834
Background: CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta(IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products(PMID:21804020). It has 5 isoforms produced by alternative splicing.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000;IHC: 1:20-1:200
Target: CASP1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat