C5AR1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: complement component 5a receptor 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 45-50 kDa
Uniprot: P21730
Gene id: 728
Background: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a(PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events(PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production(PubMed:10636859, PubMed:15153520).
Field of research: Signal Transduction, Metabolism, Immunology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF, IP
Dilution: WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Target: C5AR1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
![]()
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: complement component 5a receptor 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 45-50 kDa
Uniprot: P21730
Gene id: 728
Background: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a(PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events(PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production(PubMed:10636859, PubMed:15153520).
Field of research: Signal Transduction, Metabolism, Immunology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF, IP
Dilution: WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Target: C5AR1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat