BUB3 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: budding uninhibited by benzimidazoles 3 homolog(yeast)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight:
Uniprot: O43684
Gene id: 9184
Background: Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule(K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1
BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome(APC
C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC
C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.
Field of research: Cell Division and Proliferation
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IF
Dilution: IF: 1:20-1:200
Target: BUB3
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
![]()
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: budding uninhibited by benzimidazoles 3 homolog(yeast)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight:
Uniprot: O43684
Gene id: 9184
Background: Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule(K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1
BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome(APC
C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC
C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.
Field of research: Cell Division and Proliferation
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IF
Dilution: IF: 1:20-1:200
Target: BUB3
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat